V4 Inheritance 5

• Biologie
• Middelbare school
• vwo
• Leerjaar 4

The lesson will start once everyone has done the following:

- Open your macbook

- Open the Huntington's disease assignment

- Put away phones etc.

- Stop talking

Goals for today:

• Be able to calculate the chance of inheriting a trait/disease or of being a carrier in monohybrid and dihybrid inheritance
• Be able to name exceptions to 'normal' monohybrid inheritance (e.g. X chromosomal)
• Understand why you got the grade for the test that you did  

Complete the Huntington's Disease assignment (see Classroom)

If you haven't checked your answers to the monohybrid inheritance worksheet Part A and B yet, do this first

You have the rest of the lesson to work on the assignment.

Work individually: your own opinion matters!

Usual rules: no phones (unless permission asked), yes music.

Flexible work time:

- First priority: complete the Huntington's Assignment and hand it on on Classroom (we will discuss it this class)

- Second priority: Complete the dihybrid cross worksheet

- Optional: 

• extra exercises dihybrid cross
• choose an article about genetics to read (see Classroom)
• help your classmates

You may work together with your neighbors.

Huntington's Disease assignment: discussion

Expectations:

• Have handed in the assignment
• Have joined the lessonup
• Have the assignment open on your computer
• Give each other room to talk and be heard; listen
• Actively participate

What are the chances that the child (from the assignment) will get Huntington's disease?

Why isn't it possible to be a carrier for Huntington's?

What was the most important factor in your decision to have children or not?

Discuss with your neighbor:

1) Why does the disease primarily affect boys? (Remember, the gene is on the X-chromosome)

2) Is the allele for Duchenne's Muscular Dystrophy dominant or recessive?

What do you think dihybrid inheritance (or: a dihybrid cross) means?

Practicing dihybrid crosses

Goal: completing the dihybrid cross worksheet

If you are not sure how to do this, you can use:

- the examples on page ... of the book

- the video '...' in the classroom

Discussing the test

- First: an announcement about question 7 and 8 

- Then: take 15 minutes to look at your test results and check your grade: grade = (points/33)x9 +1.

- After that, we will discuss the most difficult questions together