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5.5 When genes change
5. It runs in the family
On inheritance, family trees, genetics and DNA
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Slide 1:
Tekstslide
Biologie
Middelbare school
vwo
Leerjaar 3
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5. It runs in the family
On inheritance, family trees, genetics and DNA
Slide 1 - Tekstslide
Draw a Punnett square showing the crossing of the F1 flowers from Mendel's pea plants.
Slide 2 - Open vraag
purple x white gives purple offspring. Purple must be dominant
P = purple
p = white
Purple F1 crossing gives purple + white flowers
F1 must be Pp
Slide 3 - Tekstslide
F1: Pp x Pp
F2: PP 25% Purple
Pp 50% Purple
pp 25% White
P
p
P
PP
Pp
p
Pp
pp
Slide 4 - Tekstslide
5.5 when genes change
What is a
mutation
?
How can a
disease
be inherited from one
generation
to the
next
?
Slide 5 - Tekstslide
Slide 6 - Video
mutations
= change in a gene or chromosome (genotype)
This may result in no/small/large change in phenotype
Slide 7 - Tekstslide
mutations
= change in a gene or chromosome (genotype)
This may result in no/small/large change in phenotype
the change can be negative/neutral/beneficial
Slide 8 - Tekstslide
mutations
Slide 9 - Tekstslide
mutations
External
caused by known
mutagens
Radiation: (eg. UV light, X-ray, radioactive decay)
Chemicals (eg. benzene in cigarette smoke)
Bacteria or viruses (eg. HPV)
Internal
DNA replication
Slide 10 - Tekstslide
mutations
Gene mutations
Defect of a gene
eg. sickle cell disease
Chromosome mutations
Change in a whole chromosome
eg. extra chromosome 21 leads to Down Syndrome
Slide 11 - Tekstslide
Definitions
A= healthy
a = sickle cell disease
Person with AA is
healthy
Person with aa has
sickle cell disease
Person with Aa is a
'carrier'
Slide 12 - Tekstslide
Read section 5.5
Do exercises 30, 31, 32 (34, 35 and 36)
Also on SOM
Slide 13 - Tekstslide
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