In deze les zitten 15 slides, met tekstslides en 1 video.
Onderdelen in deze les
Slide 1 - Tekstslide
12.6 DNA modification
Introduction
Learning objectives
Instruction DNA modification
Assignments
End of class
Slide 2 - Tekstslide
How did a human gene end up in the DNA of Herman the Bull, according to you?
Slide 3 - Tekstslide
Learning objectives
You will learn why and in what way humans alter the DNA of organisms.
You will learn why certain opponents disapprove of DNA modification.
Slide 4 - Tekstslide
DNA
gene therapy = modifying genes in order to cure a patient
Slide 5 - Tekstslide
Slide 6 - Video
Genetic modification
= the altering of an organism's DNA
genetically modified organism (GMO) = organism in which the DNA has been altered by humans
transgenic = if the new gene originates from another species
Slide 7 - Tekstslide
NL vertaling:
Producten van transgene bacteriën
Stollingsfactoren in hemofiliepatiënten
Medicijnen en hormonen
Biobrandstof van groenafval
Aspartaam, een zoetstof in light dranken
Slide 8 - Tekstslide
DNA modification
You ‘cut out’ the desired gene from the DNA of another organism, using a special enzyme.
You insert this gene into another cell by:
- injecting the gene into the cell nucleus
- using a vector as a means of transport (virus, plasmid, projectiles)
Slide 9 - Tekstslide
Viral vectors
A virus brings the DNA to a host cell.
Example: gene therapy for CF
Slide 10 - Tekstslide
Plasmids
Plasmid = circular piece of DNA that is able to replicate its own DNA independently
Used to insert a gene into a bacterium
Slide 11 - Tekstslide
Projectiles
Shooting very small golden projectiles, covered with DNA, into a cell nucleus.
Slide 12 - Tekstslide
Normal rice: No vitamin A Transgenic rice: contains vitamin A
Vitamin A deficiency causes blindness and death
Slide 13 - Tekstslide
Objections to genetic modification
The individual character and the well-being of animals are affected by genetic modification.
Unexpected effects may occur (e.g. plagues)
The pollen of genetically modified plants can also end up in traditional crops. The offspring then contains the new genes, even though you might not want it to.
Transgenic food can pose a threat to our health.
New illnesses that could be transmitted from animals to humans could develop
Slide 14 - Tekstslide
What?
Read: 12.6
Make: at least 10 assignment (make sure to make assignments from all of the different parts of instruction)
How?
In your book. You may whisper if you want to discuss an assignment with your neighbour.
Help?
Try to answer the question together. Raise your hand if you can't figure it out together.
