YR3_THV3_HW10

• Biologie
• Middelbare school
• vwo
• Leerjaar 3

Homeostasis, Health & Disease

HW LSN 10

Learning Goals:

• I understand the difference in innate and adaptive immune system.
• I understand the difference in specific and aspecific immune system.
• I can explain what barriers in the human body contribute to immunity.
• I can explain how phagocytes contribute to immunity.

Key Words:

• Innate immunity
• Adaptive immunity
• Barrier function
• Phagocyte
• Phagocytosis
• Lymphatic system
• Lymph nodes

Read pages 147 & 148 in your book and look for definitions of these words.

FOR DURING LSN 10

These notes are extra explanations. They are to help you understand the learning goals and keywords. They will be discussed during the next coming lesson you are now preparing for.

 If you want to, you can write them down, but please do not write down what you do not understand. 

Lines of defence

Adaptive immunesystem

Parts and processes of the immune system that are changing based on previous experiences

Lines of defence

The immune system counters attacks from pathogens in three lines of defense:

1. Barriers:           keeping the pathogens out

2. Phagocytes:   attacking and wiping out invaded pathogens 

3. Lymphocytes:    learning from phagocytes how to specifically                                      and effectively kill a certain type of pathogen

Line 1: Barriers

Keeping pathogens out

• skin
• mucosal membranes
• stomach acid
• antibacterial proteins

Line 1: Barriers

Mechanical barriers                   vs               Chemical barriers

Physical blockages preventing pathogens from entering the body

Attacking pathogens by means of antimicrobial molecules

Line 2: phagocytes

phagocytes are able to perform phagocytosis

different types of phagocytes

dendritic cells

macrophages

neutrophils

phagocytes that display parts of pathogen on there membranes for display and presentation

phagocytes that patrol in tissues and kill off pathogens. They can be controlled by lymphocytes (line 3)

phagocytes that kill off pathogens by killing themselves

Lymphatic system

lymph vessels, lymph nodes, bone marrow, spleen and thymus

sewage system of your body

drained tissue fluid is sent to lymph nodes for screening

here the dendritic cell presents its pathogen parts (antigens)