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Y3-THV3-Lesson 11 GKR
Homeostasis, Health & Disease
Lesson 11
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Biologie
Middelbare school
havo, vwo
Leerjaar 3
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Homeostasis, Health & Disease
Lesson 11
Slide 1 - Diapositive
This lesson
Innate immunity
Progress Pathogen project
Slide 2 - Diapositive
PATHOGENS PROJECT
How are you doing?
Any questions so far?
Do not forget:
Start writing your final report
Submission date: October 25th
Slide 3 - Diapositive
Learning goals
I understand the difference in innate and adaptive immune system
I understand the difference in specific and aspecific immune system
I can explain what barriers in the human body contribute to immunity
I can explain how phagocytes contribute to immunity
Slide 4 - Diapositive
Keywords
Innate immunity
Adaptive immunity
Barrier function
Phagocyte
Phagocytosis
Lymphatic system
Lymph nodes
Slide 5 - Diapositive
Innate immunesystem
Innate immune system:
Parts of the immune system that are present from birth
Slide 6 - Diapositive
Adaptive immunesystem
Adaptive immune system:
Parts and processes of the immune system that are changing based on previous experiences
Slide 7 - Diapositive
Lines of defence
Immune system
counters attacks from pathogens in three line
s of defense:
Barriers
: keeping the pathogens out
Phagocy
tes
:
attacking and wiping out invaded pathogens
Lymphocytes
:
learning from phagocytes how to specifically and effectively kill a certain type of pathogen
Slide 8 - Diapositive
Slide 9 - Vidéo
Slide 10 - Vidéo
Lines of defence
Slide 11 - Diapositive
Line 1: Barriers
Keeping pathogens out
Mechanical:
Physical blockages preventing pathogens from entering the body
Chemical:
Attacking pathogens by means of antimicrobial molecules
skin
mucosal membranes
stomach acid
antibacterial proteins
Slide 12 - Diapositive
Line 1: Barriers
Mechanical Barriers vs Chemical Barriers
Physical blockages preventing pathogens from entering the body
Attacking pathogens by means of antimicrobial molecules
Slide 13 - Diapositive
0
Slide 14 - Vidéo
Line 2: Phagocytes
Phagocytes
are able to perform
phagocytosis
Slide 15 - Diapositive
Line 2: Phagocytes
Phagocytes
are able to perform
phagocytosis
and to present parts of the pathogen to the adaptive immune system
Slide 16 - Diapositive
Different types of phagocytes
Dendritic cells
Macrophages
Neutrophils
Phagocytes that display parts of pathogen on there membranes for display and presentation
Phagocytes that patrol in tissues and kill off pathogens. They can be controlled by lymphocytes (line 3)
Phagocytes that kill off pathogens by killing themselves
Slide 17 - Diapositive
Overview of line 2
Line 1 fails: pathogens invade the body
Surviving tissue cells call for help
Macrophages start to devour pathogens and send out signs
Neutrophils arrive and join the battle. They massively kill off the pathogens and themselves
Proteins of the complement system start to kill pathogens by perforating them
Dendritic cells display parts of the pathogens on their membranes and travel to the lymph nodes
Activation of defence line 3: the adaptive immune system - the lymphocytes
Slide 18 - Diapositive
Lymphatic system
Sewage system of the body
Lymph vessels, lymph nodes, bone marrow, spleen and thymus
drained tissue fluid is sent to lymph nodes for screening
here the dendritic cell presents its pathogen parts (antigens)
Slide 19 - Diapositive
Inflamation
A reaction from the tissue to the signaling molecules
Slide 20 - Diapositive
A concept map
A concept map adds descriptions to links between two terms
Slide 21 - Diapositive
To what part of the immune system do these lines of defence belong?
Innate immune system
Adaptive immune system
Barriers
Phagocytes
Lymphocytes
Slide 22 - Question de remorquage
As part of innate immunity, the human body utilises mechanical and chemical immunity.
Which of the following is an example of chemical immunity?
A
Skin
B
Fluid flow in the urinary tracht
C
Stomach acid
D
Mucosal layer in the vagina
Slide 23 - Quiz
Explain how washing your skin with soap regularly is countering your immunity.
Slide 24 - Question ouverte
1
2
3
Surviving tissue cells are sending out distress molecules
Macrophages respond and start to devour the pathogens. They also send out other alarm molecules
Neutrophils respond and leave the blood vessels. They attack the pathogen by releasing toxic molecules and they kill themselves off
Slide 25 - Question de remorquage
Inflammation causes a lot of discomfort. Still it is very useful: for what purpose does tissue get inflamed?
Slide 26 - Question ouverte
What is the main 'ingredient' of pus?
A
pathogens
B
macrophages
C
neutrophils
Slide 27 - Quiz
Learning goals
I understand the difference in innate and adaptive immune system
I understand the difference in specific and aspecific immune system
I can explain what barriers in the human body contribute to immunity
I can explain how phagocytes contribute to immunity
Slide 28 - Diapositive
Keywords
Innate immunity
Adaptive immunity
Barrier function
Phagocyte
Phagocytosis
Lymphatic system
Lymph nodes
Slide 29 - Diapositive
Homework for next time
Study glossarie "YR3_CH10_HW 10" on StudyGo
Work on the final report of the Pathogen Project
Slide 30 - Diapositive
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