V4 Transcription

• Biologie
• Middelbare school
• vwo
• Leerjaar 2

Today:

• review: basics about proteins
  
• practicing translation
  
• why are proteins so important?
  
• start on homework assignment + exit ticket
  

In which cell organelle(s) do proteins get synthesized?

What are the subunits that proteins consist of called?

1. nucleic acids
2. nucleotides
3. amino acids
4. mRNA

A codon (or triplet) is ...

Translation begins at the . . .

1. RNA primer
2. promoter
3. start codon

Exercise translation part 1

• in pairs
• you receive a template strand (DNA)
• transcribe the sequence into mRNA
  
• translate the mRNA into a chain of amino acids
  

use the BINAS codon table (see Classroom)

Exercise translation part 2

• create two mutated versions of your DNA: one where you substitute a nucleotide and one where you delete or add a nucleotide
• transcribe the sequences into mRNA
• translate the sequence you received into a chain of amino acids
  

Are your new chains of amino acids different from the unmutated chain? What could this mean for your protein?

silent mutation:

a mutation that does not result in a functional change in the protein 

Why is the amino acid order so important?

Next class:

• Time for questions
  
• Option to quietly study/work on practice problems
• Is there anything else you need from me?

Homework + exit ticket

• Homework for Tuesday: assignment Amino acid order in proteins
  
• Exit ticket: What is your goal for next class?