12.6 DNA modification

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BiologieMiddelbare schoolvwoLeerjaar 3

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Slide 1 - Diapositive

12.6 DNA modification
Introduction
Learning objectives
Instruction DNA modification
Assignments
End of class

Slide 2 - Diapositive

How did a human gene end up in the DNA of Herman the Bull, according to you?

Slide 3 - Diapositive

Learning objectives
You will learn why and in what way humans alter the DNA of organisms.


You will learn why certain opponents disapprove of DNA modification.

Slide 4 - Diapositive

DNA
gene therapy = modifying genes in order to cure a patient

Slide 5 - Diapositive

Slide 6 - Vidéo

Genetic modification
= the altering of an organism's DNA

genetically modified organism (GMO) = organism in which the DNA has been altered by humans

transgenic = if the new gene originates from another species

Slide 7 - Diapositive

NL vertaling:

Producten van transgene bacteriën

  • Stollingsfactoren in hemofiliepatiënten
  • Medicijnen en hormonen
  • Biobrandstof van groenafval
  • Aspartaam, een zoetstof in light dranken

Slide 8 - Diapositive

DNA modification
  1. You ‘cut out’ the desired gene from the DNA of another organism, using a special enzyme.
  2. You insert this gene into another cell by:
    - injecting the gene into the cell nucleus
    - using a vector as a means of transport (virus, plasmid, projectiles)

Slide 9 - Diapositive

Viral vectors
A virus brings the DNA to a host cell. 

Example: gene therapy for CF

Slide 10 - Diapositive

Plasmids
Plasmid = circular piece of DNA that is able to replicate its own DNA independently

Used to insert a gene into a bacterium

Slide 11 - Diapositive

Projectiles
Shooting very small golden projectiles, covered with DNA,  into a cell nucleus.

Slide 12 - Diapositive

Normal rice: No vitamin A   Transgenic rice: contains vitamin A 
Vitamin A deficiency causes blindness and death

Slide 13 - Diapositive

Objections to genetic modification
  • The individual character and the well-being of  animals are affected by genetic modification.
  • Unexpected effects may occur (e.g. plagues)
  • The pollen of genetically modified plants can also end up in traditional crops. The offspring then contains the new genes, even though you might not want it to.
  • Transgenic food can pose a threat to our health. 
  • New illnesses that could be transmitted from animals to humans could develop




Slide 14 - Diapositive

What?
Read: 12.6
Make: at least 10 assignment (make sure to make assignments from all of the different parts of instruction)
How?
In your book. You may whisper if you want to discuss an assignment with your neighbour. 
Help?
Try to answer the question together. Raise your hand if you can't figure it out together. 
Time?
15 minutes
Finished?
Make a summary of chapter 12
Proceeds
You have finished your homework! Well done!

Slide 15 - Diapositive